Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26129994 | 0.80 | CYP11B1 (0.47) | KCNH2GRM2LMNAL3MBTL1CYP19A1 | |
| SCHEMBL31412907 | 0.78 | KCNH2 (0.40) | KCNH2LMNAL3MBTL1 | |
| SCHEMBL29348967 | 0.72 | GRM2 (0.41) | GRM2LMNAGBA1HDAC4HDAC1 | |
| SCHEMBL31637527 | 0.72 | GRM2 (0.41) | GRM2LMNAGBA1HDAC4HDAC1 | |
| SCHEMBL31434507 | 0.71 | TRAP1 (0.43) | KCNH2 | |
| SCHEMBL29348988 | 0.70 | POLB (0.44) | GRM2LMNAL3MBTL1HDAC4HDAC1 | |
| SCHEMBL31068166 | 0.70 | POLB (0.44) | GRM2LMNAL3MBTL1HDAC4HDAC1 | |
| SCHEMBL30645004 | 0.69 | CYP11B1 (0.60) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL15240751 | 0.69 | CYP11B1 (0.60) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7696003 | 0.69 | GRM2 (0.38) | GRM2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025044927-A1 | THIOPHENE SULFONYL CARBAMATE AS AT2R AGONIST, AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2025-03-06 | — | — | WO | disclosed |
| CN-119504722-A | Thiophene sulfonyl carbamate serving as AT2R agonist and application thereof | 武汉人福创新药物研发中心有限公司 | 2025-02-25 | — | — | CN | disclosed |