Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23121222 | 0.79 | LMNA (0.47) | KCNH2LMNAL3MBTL1KDM4E | |
| SCHEMBL31412914 | 0.78 | KCNH2 (0.47) | KCNH2LMNAL3MBTL1 | |
| SCHEMBL26129994 | 0.76 | CYP11B1 (0.47) | KCNH2LMNAL3MBTL1 | |
| SCHEMBL30361052 | 0.75 | LMNA (0.34) | KCNH2LMNAL3MBTL1 | |
| SCHEMBL25219157 | 0.70 | — | — | |
| SCHEMBL31434507 | 0.68 | TRAP1 (0.43) | KCNH2 | |
| SCHEMBL10446678 | 0.68 | ALDH1A1 (0.54) | KCNH2 | |
| SCHEMBL31434657 | 0.68 | GRM2 (0.38) | KCNH2LMNAL3MBTL1 | |
| SCHEMBL2281604 | 0.66 | — | — | |
| SCHEMBL31252019 | 0.66 | TLR8 (0.47) | KCNH2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025044927-A1 | THIOPHENE SULFONYL CARBAMATE AS AT2R AGONIST, AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2025-03-06 | — | — | WO | disclosed |
| CN-119504722-A | Thiophene sulfonyl carbamate serving as AT2R agonist and application thereof | 武汉人福创新药物研发中心有限公司 | 2025-02-25 | — | — | CN | disclosed |