Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.47 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 11/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474149 | 0.72 | HTR2C (0.48) | HTR2C | |
| SCHEMBL27735703 | 0.70 | CYP1A2 (0.42) | — | |
| SCHEMBL10277556 | 0.66 | KCNH2 (0.49) | HTR2CHTR2AHTR6CHRM4CHRM5 | |
| SCHEMBL10313038 | 0.66 | HTR2C (0.48) | HTR2CHTR2AHTR6CHRM4CHRM5 | |
| SCHEMBL21545792 | 0.65 | AXL (0.46) | HTR2CHTR2AHTR6CHRM4CHRM5 | |
| SCHEMBL28162014 | 0.65 | HTR2C (0.60) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL30474224 | 0.65 | CHRM4 (0.47) | HTR2CHTR2AHTR6CHRM4CHRM5 | |
| SCHEMBL12749507 | 0.65 | ABCG2 (0.38) | — | |
| SCHEMBL29260695 | 0.65 | PNMT (0.50) | HTR6HTR1ADRD2DRD3 | |
| SCHEMBL222040 | 0.65 | HTR2C (0.49) | HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343339-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2025-01-21 | — | — | CN | disclosed |