Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347184 | 0.85 | GPR3 (0.44) | GPR3PDE10AMAPK1CYP1A2ERN1 | |
| SCHEMBL5049954 | 0.82 | POLB (0.42) | GPR3PDE10ACYP1A2ERN1HSD17B10 | |
| SCHEMBL13467803 | 0.82 | GPR3 (0.48) | GPR3PDE10AMAPK1CYP1A2ERN1 | |
| SCHEMBL6215008 | 0.80 | GPR3 (0.57) | GPR3PDE10ACYP1A2ERN1HSD17B10 | |
| SCHEMBL4278260 | 0.80 | ERN1 (0.47) | GPR3PDE10AMAPK1CYP1A2ERN1 | |
| SCHEMBL4027568 | 0.80 | TDP1 (0.47) | GPR3PDE10ACYP1A2HSD17B10ALDH1A1 | |
| SCHEMBL31413138 | 0.77 | MAOA (0.52) | GPR3MAPK1CYP1A2HSD17B10ALDH1A1 | |
| SCHEMBL3892400 | 0.77 | ERN1 (0.57) | GPR3PDE10ACYP1A2ERN1HSD17B10 | |
| SCHEMBL23197722 | 0.74 | POLB (0.63) | GPR3PDE10AMAPK1CYP1A2ALDH1A1 | |
| SCHEMBL13451644 | 0.74 | PDE10A (0.41) | GPR3PDE10AMAPK1CYP1A2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343339-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2025-01-21 | — | — | CN | disclosed |