Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 18/20 | 0.63 |
| ▸ | DHODH | Q02127 | 2/20 | 0.63 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31413212 | 0.89 | PARP1 (0.63) | PARP1DHODHPARP2 | |
| SCHEMBL31413270 | 0.83 | PARP1 (0.82) | PARP1DHODHPARP2 | |
| Hydrochloric Acid SCHEMBL31413181 | 0.82 | PARP1 (0.80) | PARP1DHODHPARP2 | |
| SCHEMBL31413267 | 0.79 | PARP1 (0.72) | PARP1DHODHPARP2 | |
| SCHEMBL29790473 | 0.78 | PARP1 (0.80) | PARP1DHODHPARP2 | |
| SCHEMBL28840577 | 0.78 | PARP1 (0.80) | PARP1DHODHPARP2 | |
| SCHEMBL28840580 | 0.78 | PARP1 (0.84) | PARP1DHODHPARP2 | |
| SCHEMBL29790489 | 0.78 | PARP1 (0.84) | PARP1DHODHPARP2 | |
| SCHEMBL28840989 | 0.77 | PARP1 (0.82) | PARP1DHODHPARP2 | |
| SCHEMBL3580352 | 0.77 | AURKB (0.68) | PARP1DHODHPARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025042769-A1 | COMPOUNDS AND METHODS FOR INHIBITING POLY(ADP-RIBOSE) POLYMERASES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2025-02-27 | — | — | WO | claimed |
| WO-2025042769-A1 | COMPOUNDS AND METHODS FOR INHIBITING POLY(ADP-RIBOSE) POLYMERASES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2025-02-27 | — | — | WO | disclosed |