Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.40 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27142605 | 1.00 | MCHR1 (0.53) | MCHR1ALOX15HTTKCNQ3KCNQ2 | |
| SCHEMBL27142101 | 0.80 | PDE10A (0.48) | ALOX15HTTPDE10APDE4BHRH3 | |
| SCHEMBL31413425 | 0.80 | PDE10A (0.48) | ALOX15HTTPDE10APDE4BHRH3 | |
| SCHEMBL27146407 | 0.79 | HTT (0.48) | ALOX15HTTPDE10APIK3CAPDE4B | |
| SCHEMBL31413452 | 0.79 | HTT (0.48) | ALOX15HTTPDE10APIK3CAPDE4B | |
| SCHEMBL31413450 | 0.77 | PDE10A (0.48) | ALOX15HTTPDE10APDE4BHRH3 | |
| SCHEMBL27140318 | 0.77 | MCHR1 (0.49) | MCHR1PDE10APIK3R1PIK3CAMAP3K7 | |
| SCHEMBL27144412 | 0.77 | PDE10A (0.48) | ALOX15HTTPDE10APDE4BHRH3 | |
| SCHEMBL27139189 | 0.77 | MCHR1 (0.56) | MCHR1PDE10APIK3R1PIK3CAMAP3K7 | |
| SCHEMBL31413459 | 0.76 | ALOX15 (0.45) | ALOX15HTTPDE10APDE4BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |