Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27142101 | 1.00 | PDE10A (0.48) | PDE10AALOX15HTTHRH3ACACB | |
| SCHEMBL31413450 | 0.86 | PDE10A (0.48) | PDE10AALOX15HTTHRH3ACACB | |
| SCHEMBL27144412 | 0.86 | PDE10A (0.48) | PDE10AALOX15HTTHRH3ACACB | |
| SCHEMBL27110450 | 0.85 | PDE10A (0.53) | PDE10AALOX15HTTHRH3ACACB | |
| SCHEMBL27144759 | 0.81 | MCHR1 (0.52) | ALOX15HTTHRH3AURKANPC1 | |
| SCHEMBL20176398 | 0.80 | KDM4E (0.53) | PDE10AALOX15HTTHRH3NPC1 | |
| SCHEMBL31413370 | 0.80 | MCHR1 (0.53) | PDE10AALOX15HTTHRH3PDE4B | |
| SCHEMBL27142605 | 0.80 | MCHR1 (0.53) | PDE10AALOX15HTTHRH3PDE4B | |
| SCHEMBL12302240 | 0.80 | ALDH1A1 (0.56) | ALOX15HTTHRH3NPC1RAB9A | |
| SCHEMBL31413480 | 0.78 | ALDH1A1 (0.58) | PDE10AALOX15HTTHRH3PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |