Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.46 |
| ▸ | CA2 | P00918 | 10/20 | 0.46 |
| ▸ | CA9 | Q16790 | 8/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26245379 | 0.83 | CA1 (0.44) | CA1CA2CA9CA12MAPT | |
| SCHEMBL24408786 | 0.83 | CA1 (0.44) | CA1CA2CA9CA12MAPT | |
| SCHEMBL15805069 | 0.80 | CA1 (0.48) | CA1CA2CA9CA12MAPT | |
| SCHEMBL18202965 | 0.80 | CA1 (0.48) | CA1CA2CA9CA12MAPT | |
| SCHEMBL28741168 | 0.79 | CA1 (0.47) | CA1CA2CA9CA12PPM1B | |
| SCHEMBL26952470 | 0.79 | CA1 (0.47) | CA1CA2CA9CA12PPM1B | |
| SCHEMBL15799249 | 0.78 | CA1 (0.43) | CA1CA2CA9CA12POLB | |
| SCHEMBL1897870 | 0.77 | CA1 (0.49) | CA1CA2CA9CA12PPM1B | |
| SCHEMBL11526718 | 0.77 | CA1 (0.46) | CA1CA2CA9CA12MAPT | |
| SCHEMBL31715807 | 0.77 | CA1 (0.49) | CA1CA2CA9CA12PPM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735422-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF TREATING PHENYLKETONURIA AND OTHER AMINO ACIDURIAS | Sanofi (FR) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006827-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF TREATING PHENYLKETONURIA AND OTHER AMINO ACIDURIAS | GENZYME CORPORATION (US) | 2025-01-02 | — | — | WO | disclosed |