Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25263600 | 0.81 | SCN9A (0.48) | KDM4EALDH1A1LMNACHEK1KMT2A | |
| SCHEMBL29697410 | 0.79 | KEAP1 (0.39) | KEAP1KDM4EALDH1A1CHEK1GRM5 | |
| SCHEMBL29061490 | 0.79 | KEAP1 (0.39) | KEAP1KDM4EALDH1A1CHEK1GRM5 | |
| SCHEMBL30510116 | 0.78 | KMT2A (0.51) | KEAP1KDM4EALDH1A1LMNACHEK1 | |
| SCHEMBL25380032 | 0.78 | KMT2A (0.51) | KEAP1KDM4EALDH1A1LMNACHEK1 | |
| SCHEMBL31415329 | 0.77 | KEAP1 (0.55) | KEAP1KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL25378811 | 0.77 | KDM4E (0.45) | KEAP1KDM4EALDH1A1LMNACHEK1 | |
| SCHEMBL26199143 | 0.77 | SCN4A (0.48) | KEAP1KDM4EALDH1A1CHEK1KMT2A | |
| SCHEMBL31415382 | 0.76 | KEAP1 (0.53) | KEAP1KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL31415370 | 0.75 | KEAP1 (0.42) | KEAP1KDM4EALDH1A1LMNAGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054368-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |