Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 5/20 | 0.33 |
| ▸ | JAK1 | P23458 | 5/20 | 0.33 |
| ▸ | TYK2 | P29597 | 5/20 | 0.33 |
| ▸ | JAK3 | P52333 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415329 | 0.81 | KEAP1 (0.55) | KEAP1KMT2AMAPTKDM4ENSD2 | |
| SCHEMBL31415414 | 0.77 | KEAP1 (0.50) | KEAP1KMT2AMAPTKDM4ENSD2 | |
| SCHEMBL31241561 | 0.76 | KEAP1 (0.53) | KEAP1KMT2AMAPTKDM4ENSD2 | |
| SCHEMBL31415248 | 0.76 | KEAP1 (0.49) | KEAP1KMT2AMAPTKDM4ENSD2 | |
| SCHEMBL31415385 | 0.76 | KEAP1 (0.49) | KEAP1 | |
| SCHEMBL31415520 | 0.74 | KEAP1 (0.47) | KEAP1KMT2AMAPTKDM4ENSD2 | |
| SCHEMBL29790479 | 0.74 | KMT2A (0.53) | KEAP1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL31415362 | 0.73 | MAPT (0.46) | KMT2AMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31415565 | 0.73 | KEAP1 (0.46) | KEAP1KMT2AMAPTKDM4ENSD2 | |
| SCHEMBL31415538 | 0.72 | KEAP1 (0.45) | KEAP1KMT2AMAPTKDM4ENSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054368-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |