Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871048 | 1.00 | SIGMAR1 (0.53) | SIGMAR1OPRD1AVPR1A | |
| SCHEMBL86971 | 1.00 | SIGMAR1 (0.53) | SIGMAR1OPRD1AVPR1A | |
| Methane SCHEMBL6919510 | 0.98 | SIGMAR1 (0.51) | SIGMAR1OPRD1AVPR1A | |
| Hydrochloric Acid SCHEMBL78480 | 0.98 | SIGMAR1 (0.51) | SIGMAR1OPRD1AVPR1A | |
| Hydrochloric Acid SCHEMBL29717167 | 0.98 | SIGMAR1 (0.51) | SIGMAR1OPRD1AVPR1A | |
| Ethane SCHEMBL8577252 | 0.96 | SIGMAR1 (0.54) | SIGMAR1OPRD1AVPR1A | |
| SCHEMBL2330750 | 0.93 | SIGMAR1 (0.48) | SIGMAR1OPRD1AVPR1A | |
| Propane SCHEMBL8890366 | 0.93 | SIGMAR1 (0.51) | SIGMAR1AVPR1A | |
| Butane SCHEMBL8604221 | 0.92 | SIGMAR1 (0.50) | SIGMAR1AVPR1A | |
| SCHEMBL31059145 | 0.89 | HTR2A (0.49) | SIGMAR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747251-A1 | APOL1 INHIBITORS AND METHODS OF USE | Maze Therapeutics, Inc. (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025019479-A1 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2025-01-23 | — | — | WO | disclosed |