Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871048 | 0.96 | SIGMAR1 (0.53) | SIGMAR1AVPR1AOPRD1 | |
| SCHEMBL31415656 | 0.96 | SIGMAR1 (0.53) | SIGMAR1AVPR1AOPRD1 | |
| SCHEMBL86971 | 0.96 | SIGMAR1 (0.53) | SIGMAR1AVPR1AOPRD1 | |
| Methane SCHEMBL6919510 | 0.95 | SIGMAR1 (0.51) | SIGMAR1AVPR1AOPRD1 | |
| Hydrochloric Acid SCHEMBL29717167 | 0.95 | SIGMAR1 (0.51) | SIGMAR1AVPR1AOPRD1 | |
| Hydrochloric Acid SCHEMBL78480 | 0.95 | SIGMAR1 (0.51) | SIGMAR1AVPR1AOPRD1 | |
| Propane SCHEMBL8890366 | 0.93 | SIGMAR1 (0.51) | SIGMAR1AVPR1A | |
| Butane SCHEMBL8604221 | 0.92 | SIGMAR1 (0.50) | SIGMAR1AVPR1A | |
| SCHEMBL2330750 | 0.90 | SIGMAR1 (0.48) | SIGMAR1AVPR1AOPRD1 | |
| Hexane SCHEMBL8606727 | 0.89 | SIGMAR1 (0.48) | SIGMAR1AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837707-A | USEFUL IN TREATING ANXIETY, PSYCHOSIS, EPILEPSY, CONVULSIONS, AMNESIA, PARKINSON'S DISEASE | H. LUNDBECK A/S (DK) | 1998-11-17 | — | — | US | disclosed |
| US-5830896-A | PSYCHOLOGICAL DISORDERS; ANTIEPILEPIC AGENTS; ALZHEIMER'SAND PARKINSON?S DISEASE | H. LUNDBECK A/S (DK) | 1998-11-03 | — | — | US | disclosed |
| US-5684012-A | TREATMENT OF PSYCHOLOGICAL AND NEUROLOGICAL DISORDERS | H. LUNDBECK A/S (DK) | 1997-11-04 | — | — | US | disclosed |