SCHEMBL31415696

SCHEMBL31415696

COc1cc(O)c(CC=C(C)C)c(O)c1C(=O)/C=C/c1ccc(Br)cc1

nearest known ligand 0.84

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.84
TTR P02766 1/20 0.84
ALOX5 P09917 1/20 0.84
ABCB1 P08183 16/20 0.70
TP53 P04637 1/20 0.60
MDM2 Q00987 1/20 0.60
MEN1 O00255 1/20 0.55
LMNA P02545 1/20 0.55
MAPT P10636 1/20 0.55
MAOB P27338 1/20 0.55
KMT2A Q03164 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26539037 0.94 PDPK1 (0.93) PDPK1TTRALOX5ABCB1MEN1
SCHEMBL30630210 0.94 PDPK1 (0.93) PDPK1TTRALOX5ABCB1MEN1
Xanthohumol SCHEMBL30169731 0.91 PDPK1 (1.00) PDPK1TTRALOX5ABCB1MEN1
Xanthohumol SCHEMBL143683 0.91 PDPK1 (1.00) PDPK1TTRALOX5ABCB1MEN1
Xanthohumol SCHEMBL738122 0.91 PDPK1 (1.00) PDPK1TTRALOX5ABCB1MEN1
SCHEMBL16450254 0.90 PDPK1 (0.86) PDPK1TTRALOX5ABCB1MEN1
SCHEMBL16174029 0.89 ABCB1 (0.86) PDPK1TTRALOX5ABCB1MEN1
SCHEMBL26538024 0.89 PDPK1 (0.84) PDPK1TTRALOX5ABCB1MEN1
SCHEMBL31415709 0.88 PDPK1 (0.81) PDPK1TTRALOX5ABCB1MEN1
SCHEMBL16166320 0.87 PDPK1 (0.80) PDPK1TTRALOX5ABCB1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250221944-A1 COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT KBLUEBIO INC (KR) 2025-07-10 US disclosed
EP-4506328-A1 COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT KBlueBio Inc (KR) 2025-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250221944-A1 COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT MCL1, CRBN, BCL3 PDPK1 36/4885TTR 3886/4885ALOX5 1102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.