Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354602 | 0.78 | FFAR2 (0.42) | KMT2ASMN1; SMN2 | |
| SCHEMBL24953968 | 0.76 | MEN1 (0.66) | SCDLMNAMEN1KMT2ANPC1 | |
| SCHEMBL595893 | 0.73 | SMN1; SMN2 (0.52) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31510715 | 0.73 | PSEN1 (0.53) | SCDLMNAMEN1KMT2ANPC1 | |
| SCHEMBL24953825 | 0.70 | SCD (0.48) | SCDLMNAMEN1KMT2ANPC1 | |
| SCHEMBL31416108 | 0.69 | SCD (0.48) | SCDLMNAMEN1KMT2ANPC1 | |
| SCHEMBL15834798 | 0.69 | RAB9A (0.56) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31416104 | 0.69 | NPC1 (0.47) | SCDLMNAMEN1KMT2ANPC1 | |
| SCHEMBL24953932 | 0.68 | SCD (0.47) | SCDLMNAMEN1KMT2ANPC1 | |
| SCHEMBL24953915 | 0.68 | SCD (0.47) | SCDLMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025002360-A1 | MRGPRX2 ANTAGONIST, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 北京普祺医药科技股份有限公司 | 2025-01-02 | — | — | WO | disclosed |