Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24846095 | 0.87 | DGAT1 (0.42) | DGAT1KMT2AMEN1TSHRCYP1A2 | |
| SCHEMBL31416105 | 0.82 | SCD (0.42) | KMT2AMEN1KDM4ENPC1ALDH1A1 | |
| SCHEMBL24846119 | 0.82 | KMT2A (0.39) | DGAT1KMT2AMEN1TSHRCYP1A2 | |
| SCHEMBL24846603 | 0.81 | SMN1; SMN2 (0.39) | DGAT1KMT2AMEN1TSHRCYP1A2 | |
| SCHEMBL24846062 | 0.78 | DGAT1 (0.43) | DGAT1KMT2AMEN1TSHRCYP1A2 | |
| SCHEMBL24846089 | 0.78 | DGAT1 (0.43) | DGAT1KMT2AMEN1TSHRCYP1A2 | |
| SCHEMBL24846114 | 0.78 | KMT2A (0.48) | DGAT1KMT2AMEN1TSHRCYP1A2 | |
| SCHEMBL24846671 | 0.76 | DGAT1 (0.40) | DGAT1KMT2AMEN1TSHRCYP1A2 | |
| SCHEMBL24846672 | 0.74 | SMN1; SMN2 (0.42) | KMT2AMEN1TSHRCYP1A2CYP3A4 | |
| SCHEMBL31416112 | 0.74 | NTRK1 (0.33) | KMT2APOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025002360-A1 | MRGPRX2 ANTAGONIST, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 北京普祺医药科技股份有限公司 | 2025-01-02 | — | — | WO | disclosed |