Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31416105 | 0.78 | SCD (0.42) | ALDH1A1KMT2ALMNA | |
| SCHEMBL31416110 | 0.74 | DGAT1 (0.40) | ALDH1A1KMT2ALMNAPOLB | |
| SCHEMBL21394642 | 0.69 | GCK (0.48) | GCKALDH1A1 | |
| SCHEMBL31416109 | 0.67 | GCK (0.39) | GCKMAPK1ALDH1A1KMT2ALMNA | |
| SCHEMBL21394395 | 0.66 | KDM4E (0.49) | GCKALDH1A1 | |
| SCHEMBL21394807 | 0.66 | RAB9A (0.64) | ALDH1A1KMT2ALMNAPOLB | |
| SCHEMBL29442838 | 0.66 | RAB9A (0.64) | ALDH1A1KMT2ALMNAPOLB | |
| SCHEMBL21395009 | 0.65 | PARP1 (0.53) | MAPK1ALDH1A1KMT2ALMNA | |
| SCHEMBL21395038 | 0.65 | ABCB1 (0.41) | NTRK1GCKALDH1A1 | |
| SCHEMBL21395034 | 0.65 | ABCB1 (0.37) | NTRK1GCKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025002360-A1 | MRGPRX2 ANTAGONIST, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 北京普祺医药科技股份有限公司 | 2025-01-02 | — | — | WO | disclosed |