Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | KCNK13 | Q9HB14 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30212381 | 0.79 | GRIN2B (0.36) | EGLN1CYP1A2IKZF2KCNK13GRIN1 | |
| SCHEMBL31679362 | 0.76 | CXCR4 (0.44) | CXCR4EGLN1CYP1A2IKZF2 | |
| SCHEMBL17288868 | 0.76 | CXCR4 (0.44) | CXCR4EGLN1CYP1A2IKZF2 | |
| SCHEMBL31416849 | 0.75 | ALDH1A1 (0.40) | KCNH2MCHR1CYP1A2CYP2D6PDCD1 | |
| SCHEMBL31416731 | 0.75 | TLR8 (0.38) | KCNH2MCHR1TLR8TLR7HRH3 | |
| SCHEMBL30080477 | 0.74 | CXCR4 (0.49) | CXCR4KCNH2MCHR1PDCD1CD274 | |
| SCHEMBL29740974 | 0.70 | PDCD1 (0.35) | CXCR4CYP1A2CYP2D6PDCD1CD274 | |
| SCHEMBL24984263 | 0.69 | CXCR4 (0.54) | CXCR4HRH3 | |
| SCHEMBL30212236 | 0.69 | GRIN2B (0.37) | EGLN1CYP1A2IKZF2CD274KCNK13 | |
| SCHEMBL24046712 | 0.69 | CYP11B1 (0.34) | KCNH2MCHR1TLR8TLR7HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2026046976-A1 | PYRAZOLOPYRIDINE PHOSPHATE ESTERS FOR MODULATING SALT-INDUCIBLE KINASE (SIK) | F. HOFFMANN-LA ROCHE AG (CH) | 2026-03-05 | — | — | WO | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |