Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29311545 | 1.00 | CYP11B2 (0.42) | CYP11B2KHKRPS6KA5RPS6KA4CYP11B1 | |
| SCHEMBL15057867 | 0.78 | KHK (0.40) | CYP11B2KHKCYP11B1TRPV4ALDH1A1 | |
| SCHEMBL5212018 | 0.77 | CYP11B2 (0.41) | CYP11B2KHKCYP11B1TRPV4ALDH1A1 | |
| SCHEMBL30666087 | 0.77 | CYP11B2 (0.41) | CYP11B2KHKCYP11B1TRPV4ALDH1A1 | |
| SCHEMBL30666086 | 0.77 | CYP11B2 (0.41) | CYP11B2KHKCYP11B1TRPV4ALDH1A1 | |
| SCHEMBL30376853 | 0.77 | ALDH1A1 (0.43) | CYP11B2KHKRPS6KA5RPS6KA4TRPV4 | |
| SCHEMBL565602 | 0.77 | ALDH1A1 (0.43) | CYP11B2KHKRPS6KA5RPS6KA4TRPV4 | |
| SCHEMBL2708620 | 0.76 | RPS6KA5 (0.39) | CYP11B2KHKRPS6KA5RPS6KA4CYP11B1 | |
| SCHEMBL31575181 | 0.75 | CYP11B2 (0.41) | CYP11B2KHKRPS6KA5RPS6KA4CYP11B1 | |
| SCHEMBL286959 | 0.74 | NPSR1 (0.42) | CYP11B2RPS6KA5RPS6KA4TRPV4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |