Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31417754 | 0.85 | GRM5 (0.49) | GRM5ALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL31417750 | 0.75 | GRM5 (0.46) | GRM5ALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL31417704 | 0.75 | GRM5 (0.46) | GRM5ALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL8509535 | 0.75 | L3MBTL1 (0.46) | GRM5ALDH1A1HPGDMAOBCA12 | |
| SCHEMBL29680880 | 0.75 | L3MBTL1 (0.46) | GRM5ALDH1A1HPGDMAOBCA12 | |
| SCHEMBL26641474 | 0.73 | GRM5 (0.41) | GRM5MAOBSQORL3MBTL1 | |
| SCHEMBL27224971 | 0.72 | L3MBTL1 (0.41) | GRM5ALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL19586153 | 0.72 | L3MBTL1 (0.48) | GRM5ALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL24207703 | 0.71 | SQOR (0.45) | GRM5MAOBSQOR | |
| SCHEMBL27224944 | 0.71 | MAPT (0.43) | GRM5ALDH1A1SMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016457-A1 | NEW SUBSTITUTED HETEROCYCLIC COMPOUND AS GSPTS/MYC SIGNAL FLUX REGULATOR | 杭州德睿智药科技有限公司 | 2025-01-23 | — | — | WO | disclosed |