SCHEMBL31417705

SCHEMBL31417705

O=C(/C=N/O)Nc1cccc2c1CCC2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
SIGMAR1 Q99720 2/20 0.51
LMNA P02545 1/20 0.51
THRA P10827 1/20 0.51
THRB P10828 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 2/20 0.50
TSHR P16473 2/20 0.49
GRIN2D O15399 1/20 0.48
GRIN3B O60391 1/20 0.48
GRIN1 Q05586 1/20 0.48
GRIN2A Q12879 1/20 0.48
GRIN2B Q13224 1/20 0.48
GRIN2C Q14957 1/20 0.48
GRIN3A Q8TCU5 1/20 0.48
POLB P06746 1/20 0.47
HPGD P15428 1/20 0.47
CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11888126 1.00 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ASIGMAR1LMNA
SCHEMBL2251499 1.00 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ASIGMAR1LMNA
SCHEMBL2479933 1.00 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ASIGMAR1LMNA
SCHEMBL4829038 0.97 ALDH1A1 (0.56) ALDH1A1MEN1KMT2ASIGMAR1LMNA
SCHEMBL12359714 0.97 ALDH1A1 (0.56) ALDH1A1MEN1KMT2ASIGMAR1LMNA
SCHEMBL31565000 0.82 ALDH1A1 (0.55) ALDH1A1MEN1KMT2ASIGMAR1LMNA
SCHEMBL20456548 0.82 ALDH1A1 (0.55) ALDH1A1MEN1KMT2ASIGMAR1LMNA
SCHEMBL4395712 0.81 PNMT (0.43) ALDH1A1MEN1KMT2ALMNATHRA
SCHEMBL4395713 0.81 PNMT (0.43) ALDH1A1MEN1KMT2ALMNATHRA
SCHEMBL20456551 0.79 ALDH1A1 (0.58) ALDH1A1MEN1KMT2ASIGMAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025016457-A1 NEW SUBSTITUTED HETEROCYCLIC COMPOUND AS GSPTS/MYC SIGNAL FLUX REGULATOR 杭州德睿智药科技有限公司 2025-01-23 WO disclosed