Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31417888 | 0.80 | OPRD1 (0.38) | DGAT1CYP3A4CYP2C9CYP19A1 | |
| SCHEMBL17810272 | 0.78 | DGAT1 (0.48) | DGAT1NPC1RAB9ACYP2C19CYP3A4 | |
| SCHEMBL2123455 | 0.76 | DGAT1 (0.41) | DGAT1NPC1RAB9ACYP2C19CYP3A4 | |
| SCHEMBL29806073 | 0.75 | CYP2C19 (0.40) | DGAT1NPC1RAB9ACYP2C19CYP3A4 | |
| SCHEMBL29395303 | 0.74 | DGAT1 (0.42) | DGAT1NPC1RAB9ACYP2C19CYP1A2 | |
| SCHEMBL24306344 | 0.73 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL17810171 | 0.73 | CYP19A1 (0.39) | DGAT1CYP2C19CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL24956781 | 0.73 | TLR8 (0.43) | DGAT1CYP2C19CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL31106995 | 0.72 | CYP2A6 (0.63) | DGAT1NPC1RAB9ACYP2C19CYP3A4 | |
| SCHEMBL24955614 | 0.72 | CYP2A6 (0.63) | DGAT1NPC1RAB9ACYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747247-A1 | NOVEL FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025015420-A1 | NOVEL FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | APOGEE PHARMACEUTICALS, INC. (CA) | 2025-01-23 | — | — | WO | disclosed |