Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 9/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619282 | 0.84 | LPL (0.40) | IRAK4LPLLIPGFFAR1IDO1 | |
| SCHEMBL10174900 | 0.80 | KDR (0.56) | LPLLIPG | |
| SCHEMBL27080745 | 0.78 | KDM4E (0.34) | IRAK4LPLLIPGPRMT5WDR77 | |
| SCHEMBL20600818 | 0.78 | LPL (0.39) | IRAK4LPLLIPGFFAR1DGAT1 | |
| SCHEMBL20620665 | 0.78 | IRAK4 (0.36) | IRAK4LPLLIPGFFAR1IDO1 | |
| SCHEMBL18015432 | 0.77 | GRM5 (0.44) | IRAK4LPLLIPGPRMT5WDR77 | |
| SCHEMBL20619971 | 0.77 | IRAK4 (0.43) | IRAK4LPLLIPGFFAR1PRMT5 | |
| SCHEMBL13574212 | 0.75 | GABRG2 (0.44) | LPLLIPG | |
| SCHEMBL3189393 | 0.74 | FLT3 (0.39) | PKM | |
| SCHEMBL23089768 | 0.73 | KDM4E (0.43) | IRAK4PRMT5WDR77KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016391-A1 | THIAZOLE PYRAZINE COMPOUNDS AND USE THEREOF | 南京再明医药有限公司 | 2025-01-23 | — | — | WO | disclosed |