Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 6/20 | 0.45 |
| ▸ | CDK9 | P50750 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24071516 | 0.90 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL31389080 | 0.90 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL31389079 | 0.90 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL25528397 | 0.90 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL25528336 | 0.90 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL25218872 | 0.89 | RAB9A (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL25197545 | 0.89 | RAB9A (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL31389072 | 0.89 | RAB9A (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL25200870 | 0.89 | RAB9A (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL31200518 | 0.89 | RAB9A (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092030-A1 | ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092030-A1 | ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A | PDE2A, GUCY1A1, GCGR | NPC1 1065/4885RAB9A 960/4885SMN1; SMN2 1018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.