Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | APP | P05067 | 7/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3529446 | 1.00 | MAPT (0.70) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL2203669 | 0.87 | MAPT (0.77) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL16900694 | 0.82 | MAPT (0.70) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL4661670 | 0.82 | MAPT (0.70) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL118345 | 0.82 | MAPT (0.97) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL29096030 | 0.82 | MAPT (0.59) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL4325917 | 0.82 | MAPT (1.00) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL4257409 | 0.82 | MAPT (0.70) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| Edaravone SCHEMBL4704 | 0.81 | KMT2A (1.00) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL4322399 | 0.81 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034606-A2 | A CLINICALLY-TRANSLATABLE ROS/RNS MOLECULAR IMAGING AGENT USING A RADIOLABELED DERIVATIVE OF EDARAVONE (EDV) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2025-02-13 | — | — | WO | disclosed |