SCHEMBL2203669

SCHEMBL2203669

CC1=NN(c2ccc(C)cc2)C(=O)C1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.77
KMT2A Q03164 6/20 0.77
MEN1 O00255 5/20 0.77
ALDH1A1 P00352 5/20 0.77
TDP1 Q9NUW8 4/20 0.77
LMNA P02545 1/20 0.77
HTT P42858 1/20 0.77
KDM4E B2RXH2 5/20 0.76
GAA P10253 3/20 0.76
CYP1A2 P05177 1/20 0.76
CHRM2 P08172 1/20 0.76
CYP3A4 P08684 1/20 0.76
CHRM1 P11229 1/20 0.76
TSHR P16473 1/20 0.76
PTGS1 P23219 1/20 0.76
DRD3 P35462 1/20 0.76
SMN1; SMN2 Q16637 1/20 0.76
RECQL P46063 1/20 0.74
APP P05067 8/20 0.72
POLB P06746 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13120070 0.88 ALDH1A1 (0.62) MAPTKMT2AMEN1ALDH1A1TDP1
SCHEMBL31420004 0.87 MAPT (0.70) MAPTKMT2AMEN1ALDH1A1TDP1
SCHEMBL4661670 0.87 MAPT (0.70) MAPTKMT2AMEN1ALDH1A1TDP1
SCHEMBL4257409 0.87 MAPT (0.70) MAPTKMT2AMEN1ALDH1A1TDP1
SCHEMBL118345 0.87 MAPT (0.97) MAPTKMT2AMEN1ALDH1A1TDP1
SCHEMBL16900694 0.87 MAPT (0.70) MAPTKMT2AMEN1ALDH1A1TDP1
SCHEMBL3529446 0.87 MAPT (0.70) MAPTKMT2AMEN1ALDH1A1TDP1
SCHEMBL4325917 0.87 MAPT (1.00) MAPTKMT2AMEN1ALDH1A1TDP1
Edaravone SCHEMBL4704 0.86 KMT2A (1.00) MAPTKMT2AMEN1ALDH1A1TDP1
Edaravone SCHEMBL27972444 0.86 KMT2A (1.00) MAPTKMT2AMEN1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824740-B Method for interconversion between different pyrazolone reagent derivatives of reducing sugars 西北大学 2023-03-10 CN claimed
US-RE35801-E PYRAZOLONE DERIVATIVES MITSUBISHI CHEMICAL CORPORATION (JP) 1998-05-19 US claimed
EP-0661278-A1 Blocked polyisocyanates RHONE-POULENC CHIMIE (FR) 1995-07-05 EP claimed
EP-0208874-B1 PROPHYLACTIC AND THERAPEUTIC AGENT FOR CIRCULATORY DISORDERS MITSUBISHI KASEI CORPORATION (JP) 1993-03-24 EP claimed
US-4857542-A INHIBITOR AGAINST LIPID PEROXIDATION MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1989-08-15 US claimed
EP-0208874-A1 Prophylactic and therapeutic agent for circulatory disorders MITSUBISHI KASEI CORPORATION (JP) 1987-01-21 EP claimed
CN-118754890-A Isochroman spiro pyrazolone compound and preparation method thereof 天津科技大学 2024-10-11 CN disclosed
US-12103991-B2 Electrochemical curing of redox-active sealants and adhesives THE BOEING COMPANY (US) 2024-10-01 US disclosed
WO-2024150450-A1 COMPOSITION FOR ELECTRODE FORMATION, ADDITIVE, AND GELATION INHIBITOR 日産化学株式会社 2024-07-18 WO disclosed
WO-2024150479-A1 COMPOSITION FOR ELECTRODE FORMATION, ADDITIVE, AND GELATION INHIBITOR 日産化学株式会社 2024-07-18 WO disclosed
WO-2024150812-A1 COMPOSITION FOR ELECTRODE FORMATION, ADDITIVE, AND GELATION INHIBITOR 日産化学株式会社 2024-07-18 WO disclosed
CN-118345388-A Method for preparing pyrazolone substituted quinoxalinone derivative through electrochemical promotion 桂林理工大学 2024-07-16 CN disclosed
WO-2024110326-A1 USE OF YELLOW THERMOSTABLE METHINE DYES FOR DYEING PLASTICS LANXESS DEUTSCHLAND GMBH (DE) 2024-05-30 WO disclosed
US-4857542-A INHIBITOR AGAINST LIPID PEROXIDATION MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1989-08-15 US disclosed
EP-0208874-A1 Prophylactic and therapeutic agent for circulatory disorders MITSUBISHI KASEI CORPORATION (JP) 1987-01-21 EP disclosed
US-4527994-A Process for mass-coloring nylon with 1:2 chromium complex azo dye CIBA-GEIGY CORPORATION (US) 1985-07-09 US disclosed
EP-0138749-A2 Process for mass dyeing synthetic polyamides CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed
US-4160643-A FOR POLYMERS OF ACRYLONITRILE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-07-10 US disclosed
US-3996282-A Water-soluble quaternary ammonium dyestuffs STERLING DRUG INC. (US) 1976-12-07 US disclosed
US-3935182-A Water-soluble quaternary ammonium heterocyclic azo dyestuffs STERLING DRUG INC. (US) 1976-01-27 US disclosed