Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209579 | 1.00 | LMNA (0.49) | LMNARORCMAPTGSK3AMAPK10 | |
| SCHEMBL26085118 | 0.84 | RORC (0.49) | LMNARORCMAPTGSK3AMAPK10 | |
| SCHEMBL18785787 | 0.81 | LMNA (0.53) | LMNAMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2035487 | 0.81 | LMNA (0.68) | LMNAMAPTCYP1A2CYP2C19MEN1 | |
| SCHEMBL29728783 | 0.81 | JAK2 (0.56) | MAPTGSK3AMAPK10RIOK2NPSR1 | |
| SCHEMBL1122640 | 0.81 | JAK2 (0.56) | MAPTGSK3AMAPK10RIOK2NPSR1 | |
| SCHEMBL25240657 | 0.80 | LMNA (0.49) | LMNAMAPTRIOK2CYP1A2CYP3A4 | |
| SCHEMBL12516546 | 0.80 | LMNA (0.49) | LMNAMAPTNPSR1CYP1A2CYP3A4 | |
| SCHEMBL14809290 | 0.80 | ABL1 (0.50) | LMNARORCMAPTCYP1A2CYP3A4 | |
| SCHEMBL437390 | 0.80 | ATR (0.52) | MAPTGSK3AMAPK10RIOK2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119562812-A | Substituted N- (pyridin-2-yl) acetamide derivatives as CDK12/13 inhibitors | 奥里吉恩肿瘤学有限公司 | 2025-03-04 | — | — | CN | disclosed |