SCHEMBL31420681

SCHEMBL31420681

CC(C)(C)OC(=O)N1[C@@H](COS(C)(=O)=O)CCC12CC2

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 12/20 0.34
▸ CHRM2 P08172 1/20 0.33
▸ CHRM1 P11229 1/20 0.33
▸ CHRM3 P20309 1/20 0.33
▸ DDB1 Q16531 1/20 0.32
▸ CRBN Q96SW2 1/20 0.32
▸ NR1H2 P55055 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31421413 1.00 GPR119 (0.34) GPR119CHRM2CHRM1CHRM3DDB1
SCHEMBL18018251 0.81 NR1H2 (0.41) CHRM2CHRM1CHRM3DDB1CRBN
SCHEMBL31421521 0.81 NR1H2 (0.41) CHRM2CHRM1CHRM3DDB1CRBN
SCHEMBL21441794 0.81 NR1H2 (0.41) CHRM2CHRM1CHRM3DDB1CRBN
SCHEMBL31472942 0.78 LMNA (0.35) —
SCHEMBL31420833 0.78 CHRM2 (0.35) GPR119CHRM2CHRM1CHRM3DDB1
SCHEMBL31421279 0.78 MEN1 (0.40) GPR119CHRM2CHRM1CHRM3DDB1
SCHEMBL31420587 0.78 MEN1 (0.40) GPR119CHRM2CHRM1CHRM3DDB1
SCHEMBL31421605 0.78 CHRM2 (0.35) GPR119CHRM2CHRM1CHRM3DDB1
SCHEMBL26143905 0.77 CHRM2 (0.45) GPR119CHRM2CHRM1CHRM3NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS GPR119 3347/4885CHRM2 4776/4885CHRM1 4803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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