SCHEMBL31420802

SCHEMBL31420802

CC(=O)O[C@@H]1[C@@H](OC(=O)OC(C)(C)C)CN(C(=O)OC(C)(C)C)[C@@H]1Cc1ccc(-c2cnns2)cc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 1/20 0.34
▸ NR1H2 P55055 2/20 0.32
▸ NR1H3 Q13133 2/20 0.32
▸ PIK3CD O00329 1/20 0.31
▸ USP30 Q70CQ3 1/20 0.31
▸ GPR119 Q8TDV5 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31421443 0.90 NR1H2 (0.33) DPP4NR1H2NR1H3PIK3CDUSP30
SCHEMBL31377330 0.87 GPR119 (0.42) DPP4NR1H2NR1H3USP30GPR119
SCHEMBL31421185 0.87 DPP4 (0.35) DPP4NR1H2NR1H3GPR119
SCHEMBL31420992 0.85 MCL1 (0.35) DPP4
SCHEMBL31420706 0.85 DPP4 (0.40) DPP4NR1H2NR1H3USP30
SCHEMBL31420834 0.84 DPP4 (0.35) DPP4NR1H2NR1H3GPR119
SCHEMBL31421201 0.84 DPP4 (0.35) DPP4NR1H2NR1H3USP30GPR119
SCHEMBL31421060 0.84 USP30 (0.35) DPP4NR1H2NR1H3PIK3CDUSP30
SCHEMBL31421112 0.83 NR1H2 (0.35) DPP4NR1H2NR1H3GPR119
SCHEMBL31420677 0.82 SMN1; SMN2 (0.35) DPP4NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS DPP4 4741/4885NR1H2 2741/4885NR1H3 2939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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