SCHEMBL31421201

SCHEMBL31421201

CC(=O)O[C@@H]1[C@@H](OC(=O)OC(C)(C)C)CN(C(=O)OC(C)(C)C)[C@@H]1Cc1ccc(-c2nncs2)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 1/20 0.35
▸ GPR119 Q8TDV5 1/20 0.31
▸ NR1H2 P55055 2/20 0.31
▸ NR1H3 Q13133 2/20 0.31
▸ ABHD6 Q9BV23 1/20 0.30
▸ DAGLA Q9Y4D2 1/20 0.30
▸ UCHL1 P09936 1/20 0.30
▸ USP30 Q70CQ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31421228 0.89 DPP4 (0.33) DPP4GPR119NR1H2NR1H3ABHD6
SCHEMBL31420742 0.86 GPR119 (0.43) DPP4GPR119
SCHEMBL31377330 0.86 GPR119 (0.42) DPP4GPR119NR1H2NR1H3UCHL1
SCHEMBL31420706 0.85 DPP4 (0.40) DPP4NR1H2NR1H3USP30
SCHEMBL31420802 0.84 DPP4 (0.34) DPP4GPR119NR1H2NR1H3USP30
SCHEMBL31421112 0.83 NR1H2 (0.35) DPP4GPR119NR1H2NR1H3
SCHEMBL31421333 0.82 NPC1 (0.39) DPP4GPR119NR1H2NR1H3
SCHEMBL31421467 0.82 TACR1 (0.35) DPP4NR1H2NR1H3
SCHEMBL31420677 0.82 SMN1; SMN2 (0.35) DPP4NR1H2NR1H3
SCHEMBL31421033 0.82 TACR1 (0.42) DPP4NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS DPP4 4741/4885GPR119 3347/4885NR1H2 2741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback