Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422450 | 0.89 | GAA (0.60) | HSD17B10GAANPSR1ALDH1A1TDP1 | |
| SCHEMBL8476790 | 0.83 | HSD17B10 (0.64) | HSD17B10GAANPSR1ALDH1A1TDP1 | |
| SCHEMBL24021272 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TSHRPPARAPTGS1CYP3A4 | |
| SCHEMBL31477109 | 0.81 | HSD17B10 (0.40) | HSD17B10GAANPSR1 | |
| SCHEMBL30285852 | 0.79 | HSD17B10 (0.64) | HSD17B10GAANPSR1ALDH1A1TDP1 | |
| SCHEMBL12635572 | 0.79 | HSD17B10 (0.64) | HSD17B10GAANPSR1ALDH1A1TDP1 | |
| SCHEMBL31422550 | 0.79 | SRC (0.46) | HSD17B10GAANPSR1ALDH1A1TDP1 | |
| SCHEMBL1557719 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRPPARAPTGS1CYP3A4 | |
| SCHEMBL24021298 | 0.79 | GAA (0.68) | HSD17B10GAANPSR1ALDH1A1TDP1 | |
| SCHEMBL7093110 | 0.78 | ALDH1A1 (0.67) | HSD17B10GAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085560-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |