Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SELL | P14151 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422467 | 0.83 | HSD17B10 (0.62) | HSD17B10GAANPSR1ALDH1A1TSHR | |
| SCHEMBL5598123 | 0.81 | TTR (0.54) | GAAALDH1A1TTRPOLB | |
| SCHEMBL30776597 | 0.81 | TTR (0.54) | GAAALDH1A1TTRPOLB | |
| SCHEMBL24021298 | 0.80 | GAA (0.68) | HSD17B10GAANPSR1ALDH1A1TSHR | |
| SCHEMBL3870178 | 0.80 | HSD17B10 (0.68) | HSD17B10GAANPSR1ALDH1A1TSHR | |
| SCHEMBL7093110 | 0.79 | ALDH1A1 (0.67) | HSD17B10GAAALDH1A1HPGDPOLB | |
| SCHEMBL13205866 | 0.78 | HSD17B10 (0.70) | HSD17B10GAANPSR1ALDH1A1TSHR | |
| SCHEMBL6343545 | 0.78 | HSD17B10 (0.70) | HSD17B10GAANPSR1ALDH1A1TSHR | |
| SCHEMBL504029 | 0.78 | HSD17B10 (1.00) | HSD17B10GAAPTGS1AKR1C3AKR1C2 | |
| SCHEMBL29431167 | 0.78 | HSD17B10 (0.70) | HSD17B10GAANPSR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936097-A | ANTITUMOR AGENTS | RHONE-POULENC RORER, S.A. (FR) | 1999-08-10 | — | — | US | disclosed |