Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27338781 | 0.85 | MAPT (0.40) | CYP1A2HPGDMAPTALDH1A1CNR2 | |
| SCHEMBL21198132 | 0.84 | CYP1A2 (0.44) | CYP1A2HPGDMAPTALDH1A1CNR2 | |
| SCHEMBL29672454 | 0.83 | MAPT (0.40) | CYP1A2HPGDMAPTALDH1A1CNR2 | |
| SCHEMBL5375050 | 0.83 | CYP1A2 (0.39) | CYP1A2HPGDMAPTALDH1A1CNR2 | |
| SCHEMBL16308649 | 0.83 | MAPT (0.40) | CYP1A2HPGDMAPTALDH1A1CNR2 | |
| SCHEMBL31482836 | 0.83 | CYP1A2 (0.39) | CYP1A2HPGDMAPTALDH1A1CNR2 | |
| SCHEMBL29643977 | 0.83 | SIRT2 (0.40) | CYP1A2HPGDMAPTALDH1A1CNR2 | |
| SCHEMBL28686145 | 0.83 | SIRT2 (0.40) | CYP1A2HPGDMAPTALDH1A1CNR2 | |
| SCHEMBL22890853 | 0.82 | RET (0.37) | ALDH1A1CNR2RXRARXRBRXRG | |
| SCHEMBL29643967 | 0.82 | RET (0.37) | ALDH1A1CNR2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |