Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422872 | 0.87 | CNR2 (0.46) | CNR2 | |
| SCHEMBL31423276 | 0.83 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1LMNAMAPTCNR2 | |
| SCHEMBL31422874 | 0.78 | CNR2 (0.41) | ALDH1A1CNR2KDM4E | |
| SCHEMBL31423041 | 0.78 | CNR2 (0.41) | LMNACNR2MEN1KMT2APOLB | |
| SCHEMBL31422912 | 0.71 | CNR2 (0.36) | ALDH1A1CNR2 | |
| SCHEMBL31423089 | 0.70 | MAOB (0.51) | ALDH1A1L3MBTL1LMNAMAPTKDM4E | |
| SCHEMBL31422768 | 0.70 | MAOB (0.53) | ALDH1A1L3MBTL1LMNAMAPTKDM4E | |
| SCHEMBL31422779 | 0.69 | CNR2 (0.42) | ALDH1A1CNR2KDM4EHSD17B10GAA | |
| SCHEMBL31422835 | 0.68 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNAMAPTKDM4E | |
| SCHEMBL6339142 | 0.67 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1LMNAMAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |