Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422872 | 0.81 | CNR2 (0.46) | CNR2ALOX5APFEN1 | |
| SCHEMBL31423269 | 0.81 | LMNA (0.42) | CNR2ALDH1A1POLBPKM | |
| SCHEMBL31423247 | 0.80 | CNR2 (0.40) | CNR2ALDH1A1POLBKDM4EGAA | |
| SCHEMBL31423086 | 0.79 | CNR2 (0.39) | CNR2ALDH1A1POLBKDM4EGAA | |
| SCHEMBL31423057 | 0.76 | SERPINE1 (0.38) | ALDH1A1KDM4EGAACAMKK1CAMKK2 | |
| SCHEMBL31423108 | 0.75 | SMYD3 (0.42) | ALDH1A1POLBKDM4EGAACAMKK1 | |
| SCHEMBL31423010 | 0.74 | CAMKK2 (0.43) | POLBKDM4EFEN1CAMKK1CAMKK2 | |
| SCHEMBL31422800 | 0.74 | CNR2 (0.36) | CNR2ALDH1A1POLBKDM4EGAA | |
| SCHEMBL31423163 | 0.73 | NOTUM (0.43) | CNR2ALDH1A1POLBKDM4EGAA | |
| SCHEMBL31423273 | 0.73 | CNR2 (0.43) | CNR2ALDH1A1POLBKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |