Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 8/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.34 |
| ▸ | PRKCG | P05129 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423025 | 0.82 | MEN1 (0.38) | SMN1; SMN2MEN1KMT2ALMNASMYD3 | |
| SCHEMBL31422904 | 0.82 | MEN1 (0.35) | SMN1; SMN2MEN1KMT2ALMNAJAK2 | |
| SCHEMBL31422934 | 0.81 | MEN1 (0.41) | SMN1; SMN2MEN1KMT2ALMNASMYD3 | |
| SCHEMBL31422933 | 0.81 | KDM4E (0.47) | SMN1; SMN2MEN1KMT2ACHEK1ALDH1A1 | |
| SCHEMBL31422922 | 0.81 | LMNA (0.38) | SMN1; SMN2MEN1KMT2ALMNASMYD3 | |
| SCHEMBL31423295 | 0.81 | LMNA (0.42) | SMN1; SMN2MEN1KMT2ALMNASMYD3 | |
| SCHEMBL31422769 | 0.81 | LMNA (0.40) | SMN1; SMN2MEN1KMT2ALMNASMYD3 | |
| SCHEMBL31422776 | 0.81 | LMNA (0.42) | SMN1; SMN2MEN1KMT2ALMNASMYD3 | |
| SCHEMBL31422766 | 0.79 | KMT2A (0.39) | SMN1; SMN2MEN1KMT2ALMNASMYD3 | |
| SCHEMBL31423325 | 0.79 | HSD17B2 (0.42) | SMN1; SMN2MEN1KMT2ALMNAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |