Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | FLT1 | P17948 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 6/20 | 0.38 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423010 | 0.83 | CAMKK2 (0.43) | KDM4ERAB9ANPC1MAPT | |
| SCHEMBL31422972 | 0.83 | CAMKK2 (0.43) | KDM4ERAB9ANPC1MAPT | |
| SCHEMBL31423108 | 0.82 | SMYD3 (0.42) | KDM4EALDH1A1HPGDCHEK1PDGFRB | |
| SCHEMBL31422843 | 0.81 | SMN1; SMN2 (0.42) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31423039 | 0.78 | CAMKK2 (0.44) | KDM4E | |
| SCHEMBL31423070 | 0.77 | PIK3CA (0.37) | — | |
| SCHEMBL31422800 | 0.76 | CNR2 (0.36) | KDM4EALDH1A1HPGD | |
| SCHEMBL31423195 | 0.76 | MAOB (0.43) | KDM4ERAB9AALDH1A1NPC1KMT2A | |
| SCHEMBL31423247 | 0.76 | CNR2 (0.40) | KDM4EALDH1A1HPGD | |
| SCHEMBL31423086 | 0.75 | CNR2 (0.39) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |