Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22397168 | 0.79 | CYP1A2 (0.40) | KDM4EALDH1A1UCHL1HIF1ADGAT1 | |
| SCHEMBL5064664 | 0.78 | UCHL1 (0.43) | KDM4EALDH1A1UCHL1CA12CA2 | |
| SCHEMBL3517005 | 0.78 | UCHL1 (0.43) | ALDH1A1UCHL1GAATSHRHIF1A | |
| SCHEMBL31423090 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDMAOBCA12 | |
| SCHEMBL31422780 | 0.77 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDMAOBCA12 | |
| SCHEMBL17206222 | 0.76 | UCHL1 (0.39) | UCHL1MAOBCA12CA2CA3 | |
| SCHEMBL2782538 | 0.76 | CA1 (0.43) | KDM4EALDH1A1UCHL1CA12CA2 | |
| SCHEMBL10184702 | 0.76 | TSHR (0.42) | ALDH1A1UCHL1CA12CA2GAA | |
| SCHEMBL31423318 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDMAOBCA12 | |
| SCHEMBL14929238 | 0.75 | CA1 (0.56) | KDM4EHPGDUCHL1MAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |