Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 5/20 | 0.47 |
| ▸ | DDO | Q99489 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1369128 | 0.87 | DAO (0.50) | LCKDAODDOKDM4EALDH1A1 | |
| SCHEMBL31423274 | 0.87 | PDPK1 (0.53) | LCKDAODDOKDM4EALDH1A1 | |
| SCHEMBL1452771 | 0.83 | DAO (0.46) | LCKDAODDOKDM4EALDH1A1 | |
| Zinc Ion SCHEMBL1452758 | 0.83 | DAO (0.46) | LCKDAODDOKDM4EALDH1A1 | |
| SCHEMBL18553947 | 0.80 | DAO (0.48) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31422815 | 0.79 | ADORA2A (0.51) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL31422983 | 0.79 | HRH4 (0.46) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29805139 | 0.76 | DAO (0.42) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29804764 | 0.75 | DAO (0.47) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29390425 | 0.75 | DAO (0.58) | DAODDOKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |