Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.50 |
| ▸ | PRKX | P51817 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | MST1R | Q04912 | 1/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423096 | 0.87 | LCK (0.48) | PDPK1AURKAPLK4CHEK1DAPK3 | |
| SCHEMBL31422815 | 0.82 | ADORA2A (0.51) | FLT3CDK5CLK4DYRK1BKDM4E | |
| SCHEMBL31422983 | 0.82 | HRH4 (0.46) | PDPK1AURKAPLK4CHEK1DAPK3 | |
| SCHEMBL8821216 | 0.82 | BCAT2 (0.50) | PDPK1AURKAPLK4CHEK1DAPK3 | |
| SCHEMBL2808417 | 0.81 | DHODH (0.58) | KDM4EALDH1A1GAADAODDO | |
| SCHEMBL29415464 | 0.81 | DHODH (0.58) | KDM4EALDH1A1GAADAODDO | |
| SCHEMBL19857562 | 0.79 | PDPK1 (0.53) | PDPK1AURKAPLK4CHEK1DAPK3 | |
| SCHEMBL29696398 | 0.79 | PDPK1 (0.53) | PDPK1AURKAPLK4CHEK1DAPK3 | |
| SCHEMBL31423030 | 0.79 | GRM5 (0.38) | PDPK1AURKA | |
| SCHEMBL31423005 | 0.77 | PDPK1 (0.59) | PDPK1AURKAPLK4CHEK1DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |