Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | DDO | Q99489 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423274 | 0.82 | PDPK1 (0.53) | PARP1KDM4EALDH1A1DAODDO | |
| SCHEMBL31423242 | 0.81 | JAK2 (0.37) | PARP1KDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL3418623 | 0.79 | DAO (0.64) | HRH4KDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL31423096 | 0.79 | LCK (0.48) | PARP1KDM4EALDH1A1HPGDDAO | |
| SCHEMBL31422815 | 0.74 | ADORA2A (0.51) | HRH4PARP1KDM4EALDH1A1LMNA | |
| SCHEMBL1145047 | 0.73 | HRH4 (0.60) | HRH4KDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL31422845 | 0.71 | GRIA1 (0.41) | PARP1KDM4EALDH1A1POLBFGFR1 | |
| SCHEMBL29390425 | 0.70 | DAO (0.58) | KDM4ESMN1; SMN2ALDH1A1HPGDDAO | |
| SCHEMBL29537 | 0.70 | DAO (0.58) | KDM4ESMN1; SMN2ALDH1A1HPGDDAO | |
| SCHEMBL28330780 | 0.69 | KMT2A (0.46) | PARP1KDM4ESMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |