SCHEMBL31423230

SCHEMBL31423230

Nc1ccc2[nH]nc(-c3ccccc3)c2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DCLK1 O15075 1/20 0.65
PRKD3 O94806 1/20 0.65
MAP4K4 O95819 1/20 0.65
CHEK2 O96017 1/20 0.65
CSF1R P07333 1/20 0.65
FER P16591 1/20 0.65
CDK2 P24941 1/20 0.65
MARK3 P27448 1/20 0.65
FLT4 P35916 1/20 0.65
FLT3 P36888 1/20 0.65
MAPK9 P45984 1/20 0.65
CSNK1D P48730 1/20 0.65
CLK2 P49760 1/20 0.65
CSNK2A1 P68400 1/20 0.65
CSNK1G2 P78368 1/20 0.65
MAP4K2 Q12851 1/20 0.65
STK3 Q13188 1/20 0.65
CAMK2B Q13554 1/20 0.65
CAMK2G Q13555 1/20 0.65
DYRK1A Q13627 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4008208 1.00 DCLK1 (0.65) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL1663211 0.89 AXL (0.60) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL12193658 0.86 MKNK1 (0.61) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL5552470 0.86 AXL (0.69) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL2469031 0.83 AXL (0.55) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL4006856 0.83 AXL (0.55) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL14516332 0.82 AURKA (0.59) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL17306449 0.81 MKNK1 (0.87) DCLK1PRKD3MAP4K4CHEK2CSF1R
Hydrochloric Acid SCHEMBL27750634 0.81 AXL (0.54) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL4009086 0.79 AXL (0.55) DYRK1ATTKKDM4EAXLHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085233-A1 NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF ENSEM THERAPEUTICS, INC. (US) 2025-04-24 WO disclosed