Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.35 |
| ▸ | DDO | Q99489 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422833 | 0.83 | KDM4E (0.32) | KDM4EALDH1A1POLBGAA | |
| SCHEMBL31423234 | 0.81 | ALOX5 (0.35) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31422995 | 0.80 | CNR2 (0.33) | — | |
| SCHEMBL31422953 | 0.80 | DAO (0.35) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31423389 | 0.80 | KDM4E (0.43) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31273200 | 0.79 | DAO (0.55) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31273371 | 0.79 | DAO (0.37) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31423302 | 0.77 | MMP9 (0.36) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31273602 | 0.76 | DAO (0.39) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31273400 | 0.76 | DAO (0.39) | DAODDOKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |