Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715949 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1HPGDTDP1POLB | |
| SCHEMBL22263501 | 0.87 | PPARD (0.47) | KDM4EALDH1A1HPGDPPARDPPARA | |
| SCHEMBL29934771 | 0.85 | IKBKB (0.61) | KDM4EALDH1A1HPGDPPARDPPARA | |
| SCHEMBL6603045 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDPPARDPPARA | |
| SCHEMBL4432713 | 0.85 | IKBKB (0.61) | KDM4EALDH1A1HPGDPPARDPPARA | |
| SCHEMBL5789435 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1HPGDTDP1RAB9A | |
| SCHEMBL15945346 | 0.83 | SMN1; SMN2 (0.50) | KDM4EPPARDPPARARAB9AMAPT | |
| SCHEMBL15671177 | 0.83 | PPARD (0.45) | KDM4EALDH1A1HPGDPPARDPPARA | |
| SCHEMBL4228872 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL6604321 | 0.83 | PPARD (0.45) | KDM4EALDH1A1HPGDPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |