Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423348 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL22263501 | 0.85 | PPARD (0.47) | KDM4EALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL3715949 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL6601700 | 0.85 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL15945346 | 0.84 | SMN1; SMN2 (0.50) | KDM4EMAPTRAB9ASMN1; SMN2PPARD | |
| SCHEMBL4432713 | 0.84 | IKBKB (0.61) | KDM4EALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL29934771 | 0.84 | IKBKB (0.61) | KDM4EALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL15563826 | 0.83 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL68891 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL30201832 | 0.82 | SMN1; SMN2 (0.60) | KDM4EALDH1A1HPGDNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | claimed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | claimed |