Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423372 | 0.82 | KIF11 (0.53) | KIF11TRPV1KCNK3KCNK9 | |
| SCHEMBL6804281 | 0.79 | KIF11 (0.55) | CYP3A4CYP19A1CYP2C9KIF11KMT2A | |
| SCHEMBL31423363 | 0.77 | MEN1 (0.64) | KMT2ANPC1RAB9APTPRCPTGS1 | |
| SCHEMBL14073821 | 0.76 | KMT2A (0.55) | CYP3A4CYP19A1CYP2C9KIF11KMT2A | |
| SCHEMBL14073885 | 0.76 | KMT2A (0.55) | CYP3A4CYP19A1CYP2C9KIF11KMT2A | |
| SCHEMBL14073735 | 0.76 | KMT2A (0.61) | CYP3A4CYP19A1CYP2C9KIF11KMT2A | |
| SCHEMBL14073832 | 0.76 | KMT2A (0.57) | CYP3A4CYP19A1CYP2C9KIF11KMT2A | |
| SCHEMBL30444601 | 0.76 | KMT2A (0.62) | CYP3A4CYP19A1CYP2C9KIF11KMT2A | |
| SCHEMBL22284864 | 0.75 | CYP3A4 (0.79) | CYP3A4CYP19A1CYP2C9KIF11KMT2A | |
| SCHEMBL29478292 | 0.75 | CYP3A4 (0.79) | CYP3A4CYP19A1CYP2C9KIF11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025057074-A1 | N-ARYL BENZAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | SUVEN LIFE SCIENCES LIMITED (IN) | 2025-03-20 | — | — | WO | claimed |
| WO-2025057074-A1 | N-ARYL BENZAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | SUVEN LIFE SCIENCES LIMITED (IN) | 2025-03-20 | — | — | WO | disclosed |