Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | APOB | P04114 | 9/20 | 0.52 |
| ▸ | MTTP | P55157 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796691 | 0.88 | KIF11 (0.50) | KIF11KMT2AAPOBMTTPKDM4E | |
| SCHEMBL6805006 | 0.83 | MTTP (0.53) | APOBMTTPKDM4EGAAALDH1A1 | |
| SCHEMBL24508435 | 0.83 | APOB (0.60) | KIF11APOBMTTPKDM4EGAA | |
| SCHEMBL6804954 | 0.82 | MTTP (0.54) | APOBMTTPKDM4EGAAALDH1A1 | |
| SCHEMBL31423391 | 0.79 | CYP3A4 (0.56) | KIF11KMT2ACYP3A4CYP19A1CYP2C9 | |
| SCHEMBL30444601 | 0.78 | KMT2A (0.62) | KIF11KMT2AALDH1A1MAPTCYP3A4 | |
| SCHEMBL6645543 | 0.76 | MTTP (0.61) | APOBMTTPKDM4EGAAALDH1A1 | |
| SCHEMBL24508865 | 0.76 | CYP2C9 (0.52) | KMT2AKDM4EGAAALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6803931 | 0.75 | MTTP (0.60) | APOBMTTPKDM4EGAAALDH1A1 | |
| SCHEMBL4596430 | 0.75 | KIF11 (0.59) | KIF11TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022123039-A1 | ALDEHYDE DEHYDROGENASE INHIBITORS AND THEIR THERAPEUTIC USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2022-06-16 | — | — | WO | disclosed |
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | KIF11 4663/4885KMT2A 1496/4885APOB 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.