SCHEMBL314241

SCHEMBL314241

O=C(O)CCCCCNC(=O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.51
FTO Q9C0B1 9/20 0.51
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
CYP2C19 P33261 1/20 0.51
HTT P42858 1/20 0.51
RECQL P46063 1/20 0.51
BLM P54132 1/20 0.51
SMAD3 P84022 1/20 0.51
KMT2A Q03164 1/20 0.51
PRMT1 Q99873 1/20 0.51
ACE2 Q9BYF1 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
HDAC6 Q9UBN7 1/20 0.48
JAK2 O60674 1/20 0.47
MAPK1 P28482 1/20 0.46
NT5E P21589 1/20 0.46
LMNA P02545 1/20 0.44
POLB P06746 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31172568 0.97 ALB (0.55) ALBFTOMEN1MAPTHPGD
SCHEMBL917141 0.93 ALB (0.58) ALBFTOMEN1MAPTHPGD
SCHEMBL28607477 0.90 FTO (0.53) ALBFTOMEN1MAPTHPGD
SCHEMBL7877596 0.90 FTO (0.52) ALBFTOMEN1MAPTHPGD
SCHEMBL26030595 0.90 FTO (0.52) ALBFTOMEN1MAPTHPGD
SCHEMBL25362908 0.89 FTO (0.51) ALBFTOMEN1MAPTHPGD
SCHEMBL19835756 0.89 FTO (0.53) ALBFTOMEN1MAPTHPGD
Isothiocyanate SCHEMBL27141128 0.88 ALB (0.54) ALBFTOMEN1MAPTHPGD
SCHEMBL21549529 0.88 FTO (0.50) ALBFTOMEN1MAPTHPGD
SCHEMBL22100544 0.87 FTO (0.54) ALBFTOMEN1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1250464-B1 DETECTION OF HUMAN HEPATITIS B VIRUS SURFACE ANTIGEN MUTANTS BY SPECIFIC AMPLIFICATION AND ITS APPLICATION ON GENE CHIP GOVERNMENT OF THE REPUBLIC OF (SG) 2007-02-21 EP claimed
US-6759193-B2 SYNTHETIC OLIGONUCLEOTIDES FOR USE IN IMMUNOTHERAPY THE GOVERNMENT OF THE REPUBLIC OF SINGAPORE (SG) 2004-07-06 US claimed
US-20030003549-A1 DETECTION OF HUMAN HEPATITIS B VIRUS SURFACE ANTIGEN MUTANTS BY SPECIFIC AMPLIFICATION AND ITS APPLICATION ON GENE CHIP GOVERNMENT OF THE REPUBLIC OF SINGAPORE, THE (SG) 2003-01-02 US claimed
US-11124522-B2 Chemosensor and a method of detecting palladium ions KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2021-09-21 US disclosed
US-20200392148-A1 CHEMOSENSOR AND A METHOD OF DETECTING PALLADIUM IONS KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2020-12-17 US disclosed
US-20160024138-A1 METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES LIFE TECHNOLOGIES CORP (US) 2016-01-28 US disclosed
US-9085797-B2 Method for deblocking of labeled oligonucleotides Life Technologies Corporation (US) 2015-07-21 US disclosed
US-20140066612-A1 METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES Life Technologies Corporation (US) 2014-03-06 US disclosed
US-8524882-B2 Method for deblocking of labeled oligonucleotides Life Technologies Corporation (US) 2013-09-03 US disclosed
US-20120253028-A1 METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES Life Technologies Corporation (US) 2012-10-04 US disclosed
US-8093372-B2 Contacting with nucleophilic compound Life Technologies Corporation (US) 2012-01-10 US disclosed
US-20030120063-A1 Method for deblocking of labeled oligonucleotides INVITROGEN CORPORATION 2003-06-26 US disclosed
US-20030003549-A1 DETECTION OF HUMAN HEPATITIS B VIRUS SURFACE ANTIGEN MUTANTS BY SPECIFIC AMPLIFICATION AND ITS APPLICATION ON GENE CHIP GOVERNMENT OF THE REPUBLIC OF SINGAPORE, THE (SG) 2003-01-02 US disclosed
EP-1228076-A4 A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND AND USE THEREOF UNISEARCH LTD (AU) 2002-11-06 EP disclosed
EP-1250464-A2 DETECTION OF HUMAN HEPATITIS B VIRUS SURFACE ANTIGEN MUTANTS BY SPECIFIC AMPLIFICATION AND ITS APPLICATION ON GENE CHIP The Government of the Republic of Singapore, Attorney General's Chambers (SG) 2002-10-23 EP disclosed
WO-2002074305-A1 USE OF A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND FOR TREATING ARTHRITIS UNISEARCH LIMITED (AU) 2002-09-26 WO disclosed
EP-1228076-A1 A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND AND USE THEREOF UNISEARCH LIMITED (AU) 2002-08-07 EP disclosed
WO-2000071559-A9 METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES INVITROGEN CORP (US) 2001-06-21 WO disclosed
WO-2001021628-A1 A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND AND USE THEREOF UNISEARCH LIMITED (AU) 2001-03-29 WO disclosed
WO-2001007652-A2 DETECTION OF HUMAN HEPATITIS B VIRUS SURFACE ANTIGEN MUTANTS BY SPECIFIC AMPLIFICATION AND ITS APPLICATION ON GENE CHIP THE GOVERNMENT OF THE REPUBLIC OF SINGAPORE (SG) 2001-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120063-A1 Method for deblocking of labeled oligonucleotides DCLRE1B, DDB1, DTYMK ALB 2669/4885FTO 1256/4885MEN1 3091/4885
US-11124522-B2 Chemosensor and a method of detecting palladium ions DDT, PDCD1, PDCD10 ALB 108/4885FTO 766/4885MEN1 3564/4885
US-20120253028-A1 METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES DCLRE1B, DDB1, DTYMK ALB 2669/4885FTO 1256/4885MEN1 3091/4885
US-20200392148-A1 CHEMOSENSOR AND A METHOD OF DETECTING PALLADIUM IONS DDT, PDCD1, PDCD10 ALB 108/4885FTO 766/4885MEN1 3564/4885
US-20160024138-A1 METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES DCLRE1B, DDB1, DTYMK ALB 2669/4885FTO 1256/4885MEN1 3091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.