Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.34 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424869 | 0.89 | RHEB (0.42) | BRD4DHODHRHEB | |
| SCHEMBL31424694 | 0.88 | PDE10A (0.36) | PARP1HSD17B10MAPK1PDE3BPDE3A | |
| SCHEMBL31424768 | 0.87 | BRD4 (0.44) | PARP1BRD4BRAFRHEBALDH1A1 | |
| SCHEMBL31424599 | 0.84 | CYP11B1 (0.42) | PARP1DHODHKDM4E | |
| SCHEMBL31424636 | 0.82 | PKN1 (0.37) | HSD17B10MAPK1PDE3BPDE3APDE10A | |
| SCHEMBL31424741 | 0.80 | BRD4 (0.40) | PARP1BRD4BRAF | |
| SCHEMBL31424567 | 0.79 | HSD17B10 (0.38) | PARP1HSD17B10MAOADYRK1AKDM4E | |
| SCHEMBL31424608 | 0.78 | PARP1 (0.37) | PARP1MAPK1BRD4MAOADYRK1A | |
| SCHEMBL31424682 | 0.78 | GRIN1 (0.37) | PDE10ABRD4DHODHRHEB | |
| SCHEMBL31424857 | 0.77 | RHEB (0.38) | PARP1RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431314-A | Substituted nitrogen-containing bicyclic compounds and uses thereof | 广东东阳光药业股份有限公司 | 2025-02-14 | — | — | CN | disclosed |