Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 3/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424745 | 0.89 | GRIN1 (0.39) | CYP11B1CYP11B2GRIN1GRIN2BMEN1 | |
| SCHEMBL31424768 | 0.86 | BRD4 (0.44) | PARP1 | |
| SCHEMBL31424869 | 0.85 | RHEB (0.42) | GRIN1GRIN2BDHODH | |
| SCHEMBL31424732 | 0.84 | PARP1 (0.36) | DHODHKDM4EPARP1 | |
| SCHEMBL31424709 | 0.84 | GRIN1 (0.36) | CYP11B1CYP11B2GRIN1GRIN2BCHEK2 | |
| SCHEMBL31424741 | 0.76 | BRD4 (0.40) | LMNAHTTPARP1 | |
| SCHEMBL31424567 | 0.76 | HSD17B10 (0.38) | KMT2AKDM4ELMNAHTTPARP1 | |
| SCHEMBL31424608 | 0.75 | PARP1 (0.37) | KMT2ALMNAPARP1 | |
| SCHEMBL31424693 | 0.74 | GRIN1 (0.37) | GRIN1GRIN2BDHODH | |
| SCHEMBL31424760 | 0.74 | PARP1 (0.36) | MEN1KMT2AKDM4EHTTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431314-A | Substituted nitrogen-containing bicyclic compounds and uses thereof | 广东东阳光药业股份有限公司 | 2025-02-14 | — | — | CN | disclosed |