Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31424818 | 0.88 | DHODH (0.37) | DHODHPARP1MGAMGAASI | |
| SCHEMBL31424804 | 0.85 | DHODH (0.41) | DHODHPARP1 | |
| SCHEMBL31424859 | 0.83 | BRD4 (0.41) | DHODHPARP1TNKSTNKS2 | |
| SCHEMBL30979325 | 0.82 | PARP1 (0.50) | DHODHPARP1 | |
| SCHEMBL31424735 | 0.81 | ADORA3 (0.41) | DHODHPARP1MGAMGAASI | |
| SCHEMBL31424741 | 0.81 | BRD4 (0.40) | PARP1 | |
| SCHEMBL31424761 | 0.78 | BRD4 (0.47) | DHODHPARP1 | |
| SCHEMBL31424796 | 0.78 | MKNK1 (0.42) | DHODH | |
| SCHEMBL31424624 | 0.76 | SLC2A1 (0.40) | PARP1GAAADORA1TNKSTNKS2 | |
| SCHEMBL30979344 | 0.74 | HTT (0.41) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120020129-A | Substituted nitrogen-containing bicyclic compounds and uses thereof | 广东东阳光药业股份有限公司 | 2025-05-20 | — | — | CN | disclosed |
| CN-119431314-A | Substituted nitrogen-containing bicyclic compounds and uses thereof | 广东东阳光药业股份有限公司 | 2025-02-14 | — | — | CN | disclosed |